Beschreibung
Inhaltsangabe1 Introductory Remarks.- 2 Plasticity in the Peripheral Somatosensory Nervous System.- 2.1 Aspects of Plasticity in the Peripheral Nervous System.- 2.2 Survival and Loss of Sensory Neurons After Lesions of the Peripheral Nervous System.- 2.2.1 Effect of Crush or Transection of Peripheral Nerve on Neurons of Sensory Ganglia.- 2.2.2 Trophic Dependence of Immature Sensory Neurons on the Periphery.- 2.2.3 Effect of Peripheral Nerve Transection on Different Types of Sensory Neurons in Dorsal Root Ganglia.- 2.2.4 Effect of Peripheral Nerve Section on Fibre Composition of Dorsal Roots.- 2.2.5 Fate of the Lost neurons.- 2.2.6 Sensory Cell Loss After Chemical Lesions of Afferent Fibres.- 2.3 Collateral Sprouting of Primary Afferent Fibres in the Periphery.- 2.3.1 Collateral Reinnervation of the Skin in Adult Mammals.- 2.3.2 Collateral Sprouting in Neonates.- 2.3.3 Effect of Neural Activity on Collateral Sprouting.- 2.3.4 Collateral Sprouting of Trigeminal Afferents.- 2.3.5 Collateral Sprouting and Sensory Recovery in Man.- 2.3.6 Fate of Collateral Sprouts After Regeneration of Original Nerve.- 2.4 Regeneration of Somatic Sensory Afferent Fibres.- 2.4.1 Numbers of Axons in Nerves Regenerating After Crush or Transection.- 2.4.2 Size of Regenerated Axons.- 2.4.3 Effect of Denervation on Specialized Cutaneous Mechanoreceptors.- 2.4.4 Reinnervation of Cutaneous Receptors by Regenerating Sensory Fibres.- 2.5 Modality Specificity of Somatosensory Nerve Regeneration.- 2.5.1 Regeneration of Myelinated Afferent Fibres to Hairy Skin.- 2.5.2 Regeneration of Myelinated Afferent Fibres to Glabrous Skin.- 2.5.3 Regeneration of Unmyelinated Afferent Fibres.- 2.6 Major Conclusions.- 3 Plasticity and the Mystacial Vibrissae of Rodents.- 3.1 General Account of Pathway.- 3.2 Normal Development of the Vibrissae and Their Neural Connections to the Cerebral Cortex.- 3.3 Effects of Lesions and Manipulations in Prenatal, Neonatal and Developing Animals.- 3.3.1 Damage of the Infraorbital Nerve.- 3.3.2 Lesions to One or More Vibrissae.- 3.3.3 The Effects of Supernumerary Vibrissae.- 3.3.4 The Effects of Lesioning Unmyelinated Afferents.- 3.3.5 Hyper- and Hypostimulation of Vibrissa Afferents.- 3.3.6 Cortical Alterations.- 3.4 Plasticity in the Vibrissa System of Adult Animals.- 3.4.1 The SI Cortex.- 3.4.2 The Ventral Posterior Medial Nucleus.- 3.5 Major Conclusions.- 4 Plasticity and the Spinal Dorsal Horn (with Notes on Homologous Regions of the Trigeminal Nuclei).- 4.1 Experimental Strategies for Demonstration of Plasticity in the Dorsal Horn of the Spinal Cord and Trigeminal Nuclei.- 4.2 Overview of Dorsal Horn Organization.- 4.2.1 Laminar Cytoarchitectonic Organization.- 4.2.2 Laminar Organization of the Termination of Primary Afferent Fibres.- 4.2.3 Microanatomical Organization of Low-Threshold Cutaneous Afferents.- 4.2.4 Relation of Functional Properties to Lamination of the Dorsal Horn.- 4.2.5 Inhibitory Receptive Fields.- 4.3 Somatotopic Organization of the Dorsal Horn.- 4.3.1 Dorsal Horn Neurons.- 4.3.2 Somatotopy and Lamination.- 4.3.3 Relation of Primary Afferent Projections to Dorsal Horn Somatotopy.- 4.3.4 Relation Between Dorsal Horn Cell Dendritic Morphology and Receptive Field.- 4.4 Effect of Lesions on Somatotopic Organization.- 4.4.1 Dorsal Rhizotomy.- 4.4.2 Chronic Spinal Lesions.- 4.4.3 Peripheral Nerve Transection or Crush.- 4.5 Mechanisms Underlying the Somatotopic Reorganization of Dorsal Horn Neurons.- 4.5.1 Physiological and Pharmacological Evidence for the Existence of Normally Ineffective.- Afferent Connections.- 4.5.2 Spontaneous Changes of Receptive Fields.- 4.5.3 Plasticity of Receptive Fields Induced by Afferent Activity.- 4.5.4 Involvement of Unmyelinated Afferents in the Somatotopic Reorganization After Peripheral Nerve Injury.- 4.5.5 Sprouting of Primary Afferent Fibres and Other Neurons as a Basis for Somatotopic Reorganization.- 4.6 Plasticity of the Developing Dorsal Hor.- 4.6.1 Development of Dorsal Horn Neurons and Primary
