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ConjugationDeconjugation Reactions in Drug Metabolism and Toxicity

Handbook of Experimental Pharmacology 112

C Kauffman, Frederick /
Erschienen am 01.11.2011, Auflage: 1. Auflage
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ISBN/EAN: 9783642784316
Sprache: Englisch

Beschreibung

In-depth coverage of advances in molecular biology, indicating the importance of drug and xenobiotic conjugates as transport forms of biologically active compounds. Part One describes molecular events associated with the expression and regulation of transferases and hydrolases involved in Phase II drug conjugation and deconjugation. Part Two deals with the regulation of Phase II conjugation, while Part Three critically reviews the importance of drug conjugates in pharmacology and toxicology. An up-to-date source of information of broad interest to pharmacologists and toxicologists.

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