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Abeta Peptide and Alzheimer's Disease

Celebrating a Cetury of Research

J Barrow, Colin / H Small, /
Erschienen am 01.01.2007, Auflage: 1. Auflage
CHF 127,00
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Bibliografische Daten
ISBN/EAN: 9781852339616
Sprache: Englisch
Einband: Gebunden

Beschreibung

InhaltsangabeA Brief Introduction to the History of the ß-Amyloid Protein (Aß) of Alzheimer's Disease.- The Aßcentric Pathway of Alzheimer's Disease.- The Function of the Amyloid Precursor Protein Family.- The involvement of Aß in the neuroinflammatory response.- Amyloid ß-Peptide(1-42), Oxidative Stress, and Alzheimer's Disease.- Amyloid Toxicity, Synaptic Dysfunction and the Biochemistry of Neurodegeneration in Alzheimer's Disease.- Aß Variants and Their Impact on Amyloid Formation and Alzheimer's Disease Progression.- Copper Coordination by ß-Amyloid and the Neuropathology of Alzheimer's Disease.- Cholesterol and Alzheimer's Disease.- Amyloid ß peptide and central cholinergic neurons: involvement in normal brain function and Alzheimer's disease pathology.- Physiological and Neurotoxic Properties of Aß Peptides.- Impact of ß-Amyloid on the Tau Pathology in Tau Transgenic Mouse and Tissue Culture Models.- Glial Cells and Aß Peptides in Alzheimer's Disease Pathogenesis.- The Role of Presenilins in Abeta-Induced Cell Death in Alzheimer's Disease.- Immunotherapeutic approaches to Alzheimer's disease.- Mouse Models of Alzheimer's Disease.

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